| Host: |
Goat |
| Applications: |
Pep-ELISA/WB |
| Reactivity: |
Human/Mouse/Rat/Dog |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-Rabring 7/BCA2 (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
WB-0.3-1µg/mlELISA-antibody detection limit dilution 1:32000. |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
RNF115 |
| Gene ID: |
27246 |
| Uniprot ID: |
RN115_HUMAN |
| Immunogen Region: |
Internal |
| Accession Number: |
NP_055270.1 |
| Immunogen Sequence: |
DQDNRANERGHQTH |
| Post Translational Modifications | RING-type zinc finger-dependent and E2-dependent autoubiquitination. |
| Function | E3 ubiquitin-protein ligase that mediates E2-dependent, 'Lys-48'- and/or 'Lys-63'-linked polyubiquitination of substrates and may play a role in diverse biological processes. Through their polyubiquitination, may play a role in the endosomal trafficking and degradation of membrane receptors including EGFR, FLT3, MET and CXCR4. |
| Protein Name | E3 Ubiquitin-Protein Ligase Rnf115Ring Finger Protein 115Ring-Type E3 Ubiquitin Transferase Rnf115Rab7-Interacting Ring Finger ProteinRabring 7Zinc Finger Protein 364 |
| Database Links | Reactome: R-HSA-983168 |
| Cellular Localisation | CytoplasmCytosolThe Gtp-Bound Form Of Rab7a Recruits Rnf115 From The Cytosol Onto Late Endosomes/Lysosomes |
| Alternative Antibody Names | Anti-E3 Ubiquitin-Protein Ligase Rnf115 antibodyAnti-Ring Finger Protein 115 antibodyAnti-Ring-Type E3 Ubiquitin Transferase Rnf115 antibodyAnti-Rab7-Interacting Ring Finger Protein antibodyAnti-Rabring 7 antibodyAnti-Zinc Finger Protein 364 antibodyAnti-RNF115 antibodyAnti-ZNF364 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
