| Short Description : | Rabbit polyclonal RAB11FIP5 (354-653) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IF/ICC/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:1000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RAB11FIP5 |
| Gene ID: | 26056 |
| Uniprot ID: | RFIP5_HUMAN |
| Immunogen Region: | 354-653 |
| Immunogen Sequence: | HRSSISGSLPSSGSLQAVSS RFSEEGPRSTDDTWPRGSRS NSSSEAVLGQEELSAQAKVL APGASHPGEEEGARLPEGKP VQVATPIVASSEAVAEKEGA RKEERKPRMGLFHHHHQGLS RSELGRRSSLGEKGGPILGA SPHHSSSGEEKAKSSWFGLR EAKDPTQKPSPHPVKPLSAA PVEGSPDRKQSRSSLSIALS SGLEKLKTVTSGSIQPVTQA PQAGQMVDTKRLKDSAVLD |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 354-653 of human RAB11FIP5 (NP_056285.1). |
| Tissue Specificity | Detected at low levels in heart, brain, placenta, lung, liver, adipocytes, kidney, spleen, skeletal muscle and pancreas. |
| Post Translational Modifications | Phosphorylated on serine and threonine residues. Phosphorylation at Ser-357 is PKA-dependent. |
| Function | Rab effector involved in protein trafficking from apical recycling endosomes to the apical plasma membrane. Involved in insulin granule exocytosis. May regulate V-ATPase intracellular transport in response to extracellular acidosis. |
| Protein Name | Rab11 Family-Interacting Protein 5Rab11-Fip5Gamma-Snap-Associated Factor 1Gaf-1Phosphoprotein Pp75Rab11-Interacting Protein Rip11 |
| Database Links | |
| Cellular Localisation | CytoplasmRecycling Endosome MembranePeripheral Membrane ProteinEarly Endosome MembraneGolgi Apparatus MembraneCytoplasmic VesicleSecretory Vesicle MembraneMitochondrion Membrane |
| Alternative Antibody Names | Anti-Rab11 Family-Interacting Protein 5 antibodyAnti-Rab11-Fip5 antibodyAnti-Gamma-Snap-Associated Factor 1 antibodyAnti-Gaf-1 antibodyAnti-Phosphoprotein Pp75 antibodyAnti-Rab11-Interacting Protein Rip11 antibodyAnti-RAB11FIP5 antibodyAnti-GAF1 antibodyAnti-KIAA0857 antibodyAnti-RIP11 antibody |
Information sourced from Uniprot.org
