| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-PYCR1 (1-319) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PYCR1 |
| Gene ID: |
5831 |
| Uniprot ID: |
P5CR1_HUMAN |
| Immunogen Region: |
1-319 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-319 of human PYCR1 (NP_008838.2). |
| Immunogen Sequence: |
MSVGFIGAGQLAFALAKGFT AAGVLAAHKIMASSPDMDLA TVSALRKMGVKLTPHNKETV QHSDVLFLAVKPHIIPFILD EIGADIEDRHIVVSCAAGVT ISSIEKKLSAFRPAPRVIRC MTNTPVVVREGATVYATGTH AQVEDGRLMEQLLSSVGFCT EVEEDLIDAVTGLSGSGPAY AFTALDALADGGVKMGLPRR LAVRLGAQALLGAAKMLLHS EQHPGQLKDNVSSPGGATI |
| Function | Housekeeping enzyme that catalyzes the last step in proline biosynthesis. Can utilize both NAD and NADP, but has higher affinity for NAD. Involved in the cellular response to oxidative stress. |
| Protein Name | Pyrroline-5-Carboxylate Reductase 1 - MitochondrialP5c Reductase 1P5cr 1 |
| Database Links | Reactome: R-HSA-8964539 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Pyrroline-5-Carboxylate Reductase 1 - Mitochondrial antibodyAnti-P5c Reductase 1 antibodyAnti-P5cr 1 antibodyAnti-PYCR1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
