Anti-PYCR1 antibody (1-319) (STJ29039)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal PYCR1 (1-319) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PYCR1 |
| Gene ID | 5831 |
| Uniprot ID | P5CR1_HUMAN |
| Immunogen Region | 1-319 |
| Immunogen Sequence | MSVGFIGAGQLAFALAKGFT AAGVLAAHKIMASSPDMDLA TVSALRKMGVKLTPHNKETV QHSDVLFLAVKPHIIPFILD EIGADIEDRHIVVSCAAGVT ISSIEKKLSAFRPAPRVIRC MTNTPVVVREGATVYATGTH AQVEDGRLMEQLLSSVGFCT EVEEDLIDAVTGLSGSGPAY AFTALDALADGGVKMGLPRR LAVRLGAQALLGAAKMLLHS EQHPGQLKDNVSSPGGATI |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-319 of human PYCR1 (NP_008838.2). |
Additional Info
| Function | Oxidoreductase that catalyzes the last step in proline biosynthesis, which corresponds to the reduction of pyrroline-5-carboxylate to L-proline using NAD(P)H. At physiologic concentrations, has higher specific activity in the presence of NADH. Involved in the cellular response to oxidative stress. |
| Protein Name | Pyrroline-5-Carboxylate Reductase 1 - MitochondrialP5c Reductase 1P5cr 1 |
| Database Links | Reactome: R-HSA-8964539 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Pyrroline-5-Carboxylate Reductase 1 - Mitochondrial antibodyAnti-P5c Reductase 1 antibodyAnti-P5cr 1 antibodyAnti-PYCR1 antibody |
Information sourced from Uniprot.org