Anti-PTS antibody (1-145) (STJ28228)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal PTS (1-145) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PTS |
| Gene ID | 5805 |
| Uniprot ID | PTPS_HUMAN |
| Immunogen Region | 1-145 |
| Immunogen Sequence | MSTEGGGRRCQAQVSRRISF SASHRLYSKFLSDEENLKLF GKCNNPNGHGHNYKVVVTVH GEIDPATGMVMNLADLKKYM EEAIMQPLDHKNLDMDVPYF ADVVSTTENVAVYIWDNLQK VLPVGVLYKVKVYETDNNIV VYKGE |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-145 of human PTS (NP_000308.1). |
Additional Info
| Post Translational Modifications | Phosphorylation of Ser-19 is required for maximal enzyme activity. |
| Function | Involved in the biosynthesis of tetrahydrobiopterin, an essential cofactor of aromatic amino acid hydroxylases. Catalyzes the transformation of 7,8-dihydroneopterin triphosphate into 6-pyruvoyl tetrahydropterin. |
| Protein Name | 6-Pyruvoyl Tetrahydrobiopterin SynthasePtp SynthasePtps |
| Database Links | Reactome: R-HSA-1474151 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-6-Pyruvoyl Tetrahydrobiopterin Synthase antibodyAnti-Ptp Synthase antibodyAnti-Ptps antibodyAnti-PTS antibody |
Information sourced from Uniprot.org