| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-PTS (1-145) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PTS |
| Gene ID: |
5805 |
| Uniprot ID: |
PTPS_HUMAN |
| Immunogen Region: |
1-145 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-145 of human PTS (NP_000308.1). |
| Immunogen Sequence: |
MSTEGGGRRCQAQVSRRISF SASHRLYSKFLSDEENLKLF GKCNNPNGHGHNYKVVVTVH GEIDPATGMVMNLADLKKYM EEAIMQPLDHKNLDMDVPYF ADVVSTTENVAVYIWDNLQK VLPVGVLYKVKVYETDNNIV VYKGE |
| Post Translational Modifications | Phosphorylation of Ser-19 is required for maximal enzyme activity. |
| Function | Involved in the biosynthesis of tetrahydrobiopterin, an essential cofactor of aromatic amino acid hydroxylases. Catalyzes the transformation of 7,8-dihydroneopterin triphosphate into 6-pyruvoyl tetrahydropterin. |
| Protein Name | 6-Pyruvoyl Tetrahydrobiopterin SynthasePtp SynthasePtps |
| Database Links | Reactome: R-HSA-1474151 |
| Alternative Antibody Names | Anti-6-Pyruvoyl Tetrahydrobiopterin Synthase antibodyAnti-Ptp Synthase antibodyAnti-Ptps antibodyAnti-PTS antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
