• Anti-PTGES3 antibody (1-100) [S9MR] (STJ11102289)
  • Immunofluorescence analysis of U-2 OS cells using P23/PTGES3 Rabbit monoclonal antibody (STJ11102289) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
  • Immunofluorescence analysis of NIH-3T3 cells using P23/PTGES3 Rabbit monoclonal antibody (STJ11102289) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
  • Immunofluorescence analysis of C6 cells using P23/PTGES3 Rabbit monoclonal antibody (STJ11102289) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
  • Western blot analysis of extracts of various cell lines, using P23/PTGES3 Rabbit monoclonal antibody (STJ11102289) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 3s.

Anti-PTGES3 antibody (1-100) [S9MR] (STJ11102289)

SKU:
STJ11102289

£146.50 - £639.50
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Host: Rabbit
Applications: WB/IF
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-p23 (1-100) is suitable for use in Western Blot and Immunofluorescence research applications.
Clonality: Monoclonal
Clone ID: S9MR
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:1000-1:5000
IF/ICC 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PTGES3
Gene ID: 10728
Uniprot ID: TEBP_HUMAN
Immunogen Region: 1-100
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human P23/PTGES3 (NP_006592.3).
Immunogen Sequence: MQPASAKWYDRRDYVFIEFC VEDSKDVNVNFEKSKLTFSC LGGSDNFKHLNEIDLFHCID PNDSKHKRTDRSILCCLRKG ESGQSWPRLTKERAKLNWLS
Post Translational Modifications Proteolytically cleaved by caspase-7 (CASP7) in response to apoptosis, leading to its inactivation.
Function Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway.
Protein Name Prostaglandin E Synthase 3
Cytosolic Prostaglandin E2 Synthase
Cpges
Hsp90 Co-Chaperone
Progesterone Receptor Complex P23
Telomerase-Binding Protein P23
Database Links Reactome: R-HSA-2162123
Reactome: R-HSA-3371497
Reactome: R-HSA-3371511
Reactome: R-HSA-3371568
Reactome: R-HSA-8937144
Reactome: R-HSA-8939211
Reactome: R-HSA-9018519
Reactome: R-HSA-9679191
Cellular Localisation Cytoplasm
Alternative Antibody Names Anti-Prostaglandin E Synthase 3 antibody
Anti-Cytosolic Prostaglandin E2 Synthase antibody
Anti-Cpges antibody
Anti-Hsp90 Co-Chaperone antibody
Anti-Progesterone Receptor Complex P23 antibody
Anti-Telomerase-Binding Protein P23 antibody
Anti-PTGES3 antibody
Anti-P23 antibody
Anti-TEBP antibody

Information sourced from Uniprot.org

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