| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit monoclonal antibody anti-Prostaglandin E Synthase (42-59 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
R03-8E7 |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
50mM Tris-Glycine (pH7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Purification: |
Affinity Purified |
| Concentration: |
0.3 mg/ml |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
| Gene Symbol: |
PTGES |
| Gene ID: |
9536 |
| Uniprot ID: |
PTGES_HUMAN |
| Immunogen Region: |
42-59 aa |
| Immunogen: |
A synthetic peptide of human Prostaglandin E Synthase |
| Function | Terminal enzyme of the cyclooxygenase (COX)-2-mediated prostaglandin E2 (PGE2) biosynthetic pathway. Catalyzes the glutathione-dependent oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2) in response to inflammatory stimuli. Plays a key role in inflammation response, fever and pain. Catalyzes also the oxidoreduction of endocannabinoids into prostaglandin glycerol esters and PGG2 into 15-hydroperoxy-PGE2. In addition, displays low glutathione transferase and glutathione-dependent peroxidase activities, toward 1-chloro-2,4-dinitrobenzene and 5-hydroperoxyicosatetraenoic acid (5-HPETE), respectively. |
| Protein Name | Prostaglandin E SynthaseGlutathione Peroxidase PtgesGlutathione Transferase PtgesMicrosomal Glutathione S-Transferase 1-Like 1Mgst1-L1Microsomal Prostaglandin E Synthase 1Mpges-1P53-Induced Gene 12 Protein |
| Database Links | Reactome: R-HSA-2162123 |
| Cellular Localisation | MembraneMulti-Pass Membrane ProteinCytoplasmPerinuclear RegionColocalizes With Ptgs1/Cox-1 And Ptgs2/Cox-2 In The Perinuclear Compartment |
| Alternative Antibody Names | Anti-Prostaglandin E Synthase antibodyAnti-Glutathione Peroxidase Ptges antibodyAnti-Glutathione Transferase Ptges antibodyAnti-Microsomal Glutathione S-Transferase 1-Like 1 antibodyAnti-Mgst1-L1 antibodyAnti-Microsomal Prostaglandin E Synthase 1 antibodyAnti-Mpges-1 antibodyAnti-P53-Induced Gene 12 Protein antibodyAnti-PTGES antibodyAnti-MGST1L1 antibodyAnti-MPGES1 antibodyAnti-PGES antibodyAnti-PIG12 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
