Anti-PTCRA antibody (172-281) (STJ29230)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal PTCRA (172-281) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PTCRA |
| Gene ID | 171558 |
| Uniprot ID | PTCRA_HUMAN |
| Immunogen Region | 172-281 |
| Immunogen Sequence | LCDPAGPLPSPATTTRLRAL GSHRLHPATETGGREATSSP RPQPRDRRWGDTPPGRKPGS PVWGEGSYLSSYPTCPAQAW CSRSALRAPSSSLGAFFAGD LPPPLQAGAA |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 172-281 of human PTCRA (NP_612153.2). |
Additional Info
| Tissue Specificity | Expressed in immature but not mature T-cells. Also found in CD34+ cells from peripheral blood, CD34+ precursors from umbilical cord blood and adult bone marrow. |
| Function | Component of the pre-T-cell receptor complex (composed of PTCRA, TCRB and the CD3 complex) that has a crucial role in early T-cell development, particularly alpha-beta T cell differentiation. |
| Protein Name | Pre T-Cell Antigen Receptor AlphaPt-AlphaPtaPt-Alpha-Tcr |
| Database Links | Reactome: R-HSA-9013508 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinCell Membrane |
| Alternative Antibody Names | Anti-Pre T-Cell Antigen Receptor Alpha antibodyAnti-Pt-Alpha antibodyAnti-Pta antibodyAnti-Pt-Alpha-Tcr antibodyAnti-PTCRA antibody |
Information sourced from Uniprot.org