| Short Description : | Rabbit polyclonal PTCRA (172-281) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PTCRA |
| Gene ID: | 171558 |
| Uniprot ID: | PTCRA_HUMAN |
| Immunogen Region: | 172-281 |
| Immunogen Sequence: | LCDPAGPLPSPATTTRLRAL GSHRLHPATETGGREATSSP RPQPRDRRWGDTPPGRKPGS PVWGEGSYLSSYPTCPAQAW CSRSALRAPSSSLGAFFAGD LPPPLQAGAA |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 172-281 of human PTCRA (NP_612153.2). |
| Tissue Specificity | Expressed in immature but not mature T-cells. Also found in CD34+ cells from peripheral blood, CD34+ precursors from umbilical cord blood and adult bone marrow. |
| Function | Component of the pre-T-cell receptor complex (composed of PTCRA, TCRB and the CD3 complex) that has a crucial role in early T-cell development, particularly alpha-beta T cell differentiation. |
| Protein Name | Pre T-Cell Antigen Receptor AlphaPt-AlphaPtaPt-Alpha-Tcr |
| Database Links | Reactome: R-HSA-9013508 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinCell Membrane |
| Alternative Antibody Names | Anti-Pre T-Cell Antigen Receptor Alpha antibodyAnti-Pt-Alpha antibodyAnti-Pta antibodyAnti-Pt-Alpha-Tcr antibodyAnti-PTCRA antibody |
Information sourced from Uniprot.org
