Western Blot (WB): Various whole cell lysates were separated by 10% SDS-PAGE, and the membrane was blotted with STJA0038956

Anti-PSMD11 antibody (250-350) [PTR1354] (STJA0038956)

Name: Anti-PSMD11 antibody (250-350) [PTR1354] (STJA0038956)
SKU: STJA0038956
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityMonoclonal

HostMouse

ConjugationUnconjugated

IsotypeIgG3k

ImmunogenSynthesized peptide derived from human protein.AA range:250-350

STJA0038956

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General Information

Short Description	Mouse monoclonal anti-26s Proteasome Non-Atpase Regulatory Subunit 11 (250-350) for use in WB, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/IF/ELISA
Host	Mouse
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Clonality	Monoclonal
Clone ID	PTR1354
Isotype	IgG3k
Conjugation	Unconjugated
Purification	Protein G
Dilution Range	WB 1:500-2000 IF 1:100-500 ELISA 1:1000-5000
Formulation	PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene Symbol	PSMD11
Gene ID	5717
Uniprot ID	PSD11_HUMAN
Immunogen	Synthesized peptide derived from human protein.AA range:250-350
Immunogen Region	250-350
Specificity	This antibody detects endogenous levels of PSMD11.

Additional Info

Post Translational Modifications	Phosphorylated by AMPK.
Function	Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. In the complex, PSMD11 is required for proteasome assembly. Plays a key role in increased proteasome activity in embryonic stem cells (ESCs): its high expression in ESCs promotes enhanced assembly of the 26S proteasome, followed by higher proteasome activity.
Protein Name	26s Proteasome Non-Atpase Regulatory Subunit 11 26s Proteasome Regulatory Subunit Rpn6 26s Proteasome Regulatory Subunit S9 26s Proteasome Regulatory Subunit P44.5
Database Links	Reactome: R-HSA-1169091 Reactome: R-HSA-1234176 Reactome: R-HSA-1236974 Reactome: R-HSA-1236978 Reactome: R-HSA-174084 Reactome: R-HSA-174113 Reactome: R-HSA-174154 Reactome: R-HSA-174178 Reactome: R-HSA-174184 Reactome: R-HSA-180534 Reactome: R-HSA-180585 Reactome: R-HSA-187577 Reactome: R-HSA-195253 Reactome: R-HSA-202424 Reactome: R-HSA-211733 Reactome: R-HSA-2467813 Reactome: R-HSA-2871837 Reactome: R-HSA-349425 Reactome: R-HSA-350562 Reactome: R-HSA-382556 Reactome: R-HSA-450408 Reactome: R-HSA-4608870 Reactome: R-HSA-4641257 Reactome: R-HSA-4641258 Reactome: R-HSA-5358346 Reactome: R-HSA-5362768 Reactome: R-HSA-5607761 Reactome: R-HSA-5607764 Reactome: R-HSA-5610780 Reactome: R-HSA-5610783 Reactome: R-HSA-5610785 Reactome: R-HSA-5632684 Reactome: R-HSA-5658442 Reactome: R-HSA-5668541 Reactome: R-HSA-5676590 Reactome: R-HSA-5678895 Reactome: R-HSA-5687128 Reactome: R-HSA-5689603 Reactome: R-HSA-5689880 Reactome: R-HSA-6798695 Reactome: R-HSA-68867 Reactome: R-HSA-68949 Reactome: R-HSA-69017 Reactome: R-HSA-69481 Reactome: R-HSA-69601 Reactome: R-HSA-75815 Reactome: R-HSA-8852276 Reactome: R-HSA-8854050 Reactome: R-HSA-8939236 Reactome: R-HSA-8939902 Reactome: R-HSA-8941858 Reactome: R-HSA-8948751 Reactome: R-HSA-8951664 Reactome: R-HSA-9010553 Reactome: R-HSA-9020702 Reactome: R-HSA-9604323 Reactome: R-HSA-9755511 Reactome: R-HSA-9762114 Reactome: R-HSA-9824272 Reactome: R-HSA-983168 Reactome: R-HSA-9907900
Cellular Localisation	Nucleus Cytoplasm Cytosol
Alternative Antibody Names	Anti-26s Proteasome Non-Atpase Regulatory Subunit 11 antibody Anti-26s Proteasome Regulatory Subunit Rpn6 antibody Anti-26s Proteasome Regulatory Subunit S9 antibody Anti-26s Proteasome Regulatory Subunit P44.5 antibody Anti-PSMD11 antibody

Information sourced from Uniprot.org

Citations

View product citations for antibody STJA0038956 on CiteAb