• Western blot analysis of lysates from A549 cells, using KPSH1 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using PSK-H1 Polyclonal Antibody

Anti-PSKH1 antibody (261-310 aa) (STJ95248)

SKU:
STJ95248

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Serine/threonine-protein kinase H1 (261-310 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:20000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PSKH1
Gene ID: 5681
Uniprot ID: KPSH1_HUMAN
Immunogen Region: 261-310 aa
Specificity: PSK-H1 Polyclonal Antibody detects endogenous levels of PSK-H1 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human KPSH1 at the amino acid range 261-310
Post Translational Modifications Autophosphorylated on serine residues. Myristoylated. Required for membrane association. Prerequisite for palmitoylation to occur. Palmitoylated.
Function May be a SFC-associated serine kinase (splicing factor compartment-associated serine kinase) with a role in intranuclear SR protein (non-snRNP splicing factors containing a serine/arginine-rich domain) trafficking and pre-mRNA processing.
Protein Name Serine/Threonine-Protein Kinase H1
Protein Serine Kinase H1
Psk-H1
Cellular Localisation Golgi Apparatus
Cytoplasm
Cytoskeleton
Microtubule Organizing Center
Centrosome
Nucleus Speckle
Endoplasmic Reticulum Membrane
Lipid-Anchor
Cell Membrane
Localized In The Brefeldin A-Sensitive Golgi Compartment
At Centrosomes
In The Nucleus With A Somewhat Speckle-Like Presence
Membrane-Associated To The Endoplasmic Reticulum (Er) And The Plasma Membrane (Pm)
And More Diffusely In The Cytoplasm
Found To Concentrate In Splicing Factor Compartments (Sfcs) Within The Nucleus Of Interphase Cells
The Acylation-Negative Form May Be Only Cytoplasmic And Nuclear
Acylation Seems To Allow The Sequestering To The Intracellular Membranes
Myristoylation May Mediate Targeting To The Intracellular Non-Golgi Membranes And Palmitoylation May Mediate The Targeting To The Golgi Membranes
Dual Acylation Is Required To Stabilize The Interaction With Golgi Membranes
Alternative Antibody Names Anti-Serine/Threonine-Protein Kinase H1 antibody
Anti-Protein Serine Kinase H1 antibody
Anti-Psk-H1 antibody
Anti-PSKH1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance