Host: |
Rabbit |
Applications: |
WB/IHC/IF/ELISA |
Reactivity: |
Human/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Serine/threonine-protein kinase H1 (261-310 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-1:2000IHC 1:100-1:300ELISA 1:20000IF 1:50-200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
PSKH1 |
Gene ID: |
5681 |
Uniprot ID: |
KPSH1_HUMAN |
Immunogen Region: |
261-310 aa |
Specificity: |
PSK-H1 Polyclonal Antibody detects endogenous levels of PSK-H1 protein. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from the human KPSH1 at the amino acid range 261-310 |
Post Translational Modifications | Autophosphorylated on serine residues. Myristoylated. Required for membrane association. Prerequisite for palmitoylation to occur. Palmitoylated. |
Function | May be a SFC-associated serine kinase (splicing factor compartment-associated serine kinase) with a role in intranuclear SR protein (non-snRNP splicing factors containing a serine/arginine-rich domain) trafficking and pre-mRNA processing. |
Protein Name | Serine/Threonine-Protein Kinase H1Protein Serine Kinase H1Psk-H1 |
Cellular Localisation | Golgi ApparatusCytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeNucleus SpeckleEndoplasmic Reticulum MembraneLipid-AnchorCell MembraneLocalized In The Brefeldin A-Sensitive Golgi CompartmentAt CentrosomesIn The Nucleus With A Somewhat Speckle-Like PresenceMembrane-Associated To The Endoplasmic Reticulum (Er) And The Plasma Membrane (Pm)And More Diffusely In The CytoplasmFound To Concentrate In Splicing Factor Compartments (Sfcs) Within The Nucleus Of Interphase CellsThe Acylation-Negative Form May Be Only Cytoplasmic And NuclearAcylation Seems To Allow The Sequestering To The Intracellular MembranesMyristoylation May Mediate Targeting To The Intracellular Non-Golgi Membranes And Palmitoylation May Mediate The Targeting To The Golgi MembranesDual Acylation Is Required To Stabilize The Interaction With Golgi Membranes |
Alternative Antibody Names | Anti-Serine/Threonine-Protein Kinase H1 antibodyAnti-Protein Serine Kinase H1 antibodyAnti-Psk-H1 antibodyAnti-PSKH1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance