Anti-PRRT2 antibody (20-130) (STJ118467)

Name: Anti-PRRT2 antibody (20-130) (STJ118467)
SKU: STJ118467
Availability: InStock

⇓ Datasheet ⇓ SDS Citations

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ118467

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Short Description	Rabbit polyclonal PRRT2 (20-130) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/ELISA
Host	Rabbit
Reactivity	Human/Mouse
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	PRRT2
Gene ID	112476
Uniprot ID	PRRT2_HUMAN
Immunogen Region	20-130
Immunogen Sequence	VPGEGPGHSEAETGPPQVLA GVPDQPEAPQPGPNTTAAPV DSGPKAGLAPETTETPAGAS ETAQATDLSLSPGGESKANC SPEDPCQETVSKPEVSKEAT ADQGSRLESAA
Specificity	Recombinant fusion protein containing a sequence corresponding to amino acids 20-130 of human PRRT2 (NP_660282.2).

Function	As a component of the outer core of AMPAR complex, may be involved in synaptic transmission in the central nervous system. In hippocampal neurons, in presynaptic terminals, plays an important role in the final steps of neurotransmitter release, possibly by regulating Ca(2+)-sensing. In the cerebellum, may inhibit SNARE complex formation and down-regulate short-term facilitation.
Protein Name	Proline-Rich Transmembrane Protein 2 Dispanin Subfamily B Member 3 Dspb3
Database Links
Cellular Localisation	Cell Membrane Single-Pass Membrane Protein Presynaptic Cell Membrane Synapse Cell Projection Axon Cytoplasmic Vesicle Secretory Vesicle Synaptic Vesicle Membrane Postsynaptic Density Membrane Dendritic Spine
Alternative Antibody Names	Anti-Proline-Rich Transmembrane Protein 2 antibody Anti-Dispanin Subfamily B Member 3 antibody Anti-Dspb3 antibody Anti-PRRT2 antibody

Information sourced from Uniprot.org