• Western blot analysis of various lysates using PRRT2 Rabbit polyclonal antibody (STJ118467) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.

Anti-PRRT2 antibody (20-130) (STJ118467)

SKU:
STJ118467

£112.50 - £522.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-PRRT2 (20-130) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PRRT2
Gene ID: 112476
Uniprot ID: PRRT2_HUMAN
Immunogen Region: 20-130
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 20-130 of human PRRT2 (NP_660282.2).
Immunogen Sequence: VPGEGPGHSEAETGPPQVLA GVPDQPEAPQPGPNTTAAPV DSGPKAGLAPETTETPAGAS ETAQATDLSLSPGGESKANC SPEDPCQETVSKPEVSKEAT ADQGSRLESAA
Function As a component of the outer core of AMPAR complex, may be involved in synaptic transmission in the central nervous system. In hippocampal neurons, in presynaptic terminals, plays an important role in the final steps of neurotransmitter release, possibly by regulating Ca(2+)-sensing. In the cerebellum, may inhibit SNARE complex formation and down-regulate short-term facilitation.
Protein Name Proline-Rich Transmembrane Protein 2
Dispanin Subfamily B Member 3
Dspb3
Cellular Localisation Cell Membrane
Single-Pass Membrane Protein
Presynaptic Cell Membrane
Synapse
Cell Projection
Axon
Cytoplasmic Vesicle
Secretory Vesicle
Synaptic Vesicle Membrane
Postsynaptic Density Membrane
Dendritic Spine
Alternative Antibody Names Anti-Proline-Rich Transmembrane Protein 2 antibody
Anti-Dispanin Subfamily B Member 3 antibody
Anti-Dspb3 antibody
Anti-PRRT2 antibody

Information sourced from Uniprot.org

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