Anti-PRPF31 antibody (1-200) (STJ28299)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal PRPF31 (1-200) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IHC-P:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.09% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PRPF31 |
| Gene ID | 26121 |
| Uniprot ID | PRP31_HUMAN |
| Immunogen Region | 1-200 |
| Immunogen Sequence | MSLADELLADLEEAAEEEEG GSYGEEEEEPAIEDVQEETQ LDLSGDSVKTIAKLWDSKMF AEIMMKIEEYISKQAKASEV MGPVEAAPEYRVIVDANNLT VEIENELNIIHKFIRDKYSK RFPELESLVPNALDYIRTVK ELGNSLDKCKNNENLQQILT NATIMVVSVTASTTQGQQLS EEELERLEEACDMALELNAS |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human PRPF31 (NP_056444.3). |
Additional Info
| Tissue Specificity | Ubiquitously expressed. |
| Post Translational Modifications | Phosphorylated by PRP4K during spliceosome assembly. |
| Function | Involved in pre-mRNA splicing as component of the spliceosome. Required for the assembly of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome. |
| Protein Name | U4/U6 Small Nuclear Ribonucleoprotein Prp31Pre-Mrna-Processing Factor 31Serologically Defined Breast Cancer Antigen Ny-Br-99U4/U6 Snrnp 61 Kda ProteinProtein 61kHprp31 |
| Database Links | Reactome: R-HSA-72163 |
| Cellular Localisation | NucleusNucleus SpeckleCajal BodyPredominantly Found In Speckles And In Cajal Bodies |
| Alternative Antibody Names | Anti-U4/U6 Small Nuclear Ribonucleoprotein Prp31 antibodyAnti-Pre-Mrna-Processing Factor 31 antibodyAnti-Serologically Defined Breast Cancer Antigen Ny-Br-99 antibodyAnti-U4/U6 Snrnp 61 Kda Protein antibodyAnti-Protein 61k antibodyAnti-Hprp31 antibodyAnti-PRPF31 antibodyAnti-PRP31 antibody |
Information sourced from Uniprot.org