Anti-Progesterone antibody [EBS-O-049] (STJ16102598)

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STJ16102598
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Short Description :Mouse monoclonal anti-Progesterone for use in ELISA in All Species samples. Datasheet included with dilution recommendations, and related reagents.
Applications:ELISA
Host:Mouse
Reactivity:All Species
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :EBS-O-049
Isotype:IgG1k
Conjugation:Unconjugated
Concentration:Can be provided as 100 µg/mL, 500 µg/mL or 1mg/mL.
Purification:Affinity purified from tissue culture.
Dilution Range:ELISA (solid phase: 0, 1-100 µg/ml; tracer: 0, 001-100 µg/ml for 30 min at RT).
Formulation:PBS with 0.02% Sodium Azide.
Storage Instruction:Store for up to 1 year at 2-8°C upon receipt.
Gene Symbol:PGRMC2
Gene ID:10424
Uniprot ID:PGRC2_HUMAN
Immunogen:A BALB/c mouse was immunized with Progesterone-11a-hemisuccinate conjugated to BSA (Progesterone-11a-HMS-BSA). Fusion partner: X63-Ag8-653.
Function Required for the maintenance of uterine histoarchitecture and normal female reproductive lifespan. May serve as a universal non-classical progesterone receptor in the uterus (Probable). Intracellular heme chaperone required for delivery of labile, or signaling heme, to the nucleus. Plays a role in adipocyte function and systemic glucose homeostasis. In brown fat, which has a high demand for heme, delivery of labile heme in the nucleus regulates the activity of heme-responsive transcriptional repressors such as NR1D1 and BACH1.
Protein Name Membrane-Associated Progesterone Receptor Component 2
Progesterone Membrane-Binding Protein
Steroid Receptor Protein Dg6
Database Links Reactome: R-HSA-8980692
Reactome: R-HSA-9013404
Reactome: R-HSA-9013405
Reactome: R-HSA-9013408
Reactome: R-HSA-9013423
Reactome: R-HSA-9707616
Cellular Localisation Membrane
Single-Pass Membrane Protein
Nucleus Envelope
Endoplasmic Reticulum
Secreted
Alternative Antibody Names Anti-Membrane-Associated Progesterone Receptor Component 2 antibody
Anti-Progesterone Membrane-Binding Protein antibody
Anti-Steroid Receptor Protein Dg6 antibody
Anti-PGRMC2 antibody
Anti-DG6 antibody
Anti-PMBP antibody

Information sourced from Uniprot.org