Anti-Pre-pro-AVP antibody (STJA0005237)

SKU:
STJA0005237-100

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Host: Rabbit
Applications: WB/IHC/ICC
Reactivity: Human/Mouse/Rat/Non-Human Primates
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Pre-pro-Vasopressin is suitable for use in Western Blot, Immunohistochemistry and Immunocytochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 10 mM HEPES (pH 7.5) , 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.
Purification: Antigen Affinity Purified from Pooled Serum
Dilution Range: WB 1:1000
IHC 1:1000
ICC 1:1000
IP
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: AVP
Gene ID: 551
Uniprot ID: NEU2_HUMAN
Specificity: Specific for locally produced levels of the ~ 20 kDa uncleaved pre-pro-vasopressin protein. Immunolabeling of the uncleaved pre-pro-vasopressin protein band is completely blocked by preadsorption of the antibody with the peptide used as antigen.
Immunogen: Synthetic peptide corresponding to key amino acid residues surrounding the cleavage sites for the human vasopressin precursor peptide, conjugated to keyhole limpet hemocyanin (KLH).
Function Neurophysin 2: Specifically binds vasopressin. Arg-vasopressin: Has a direct antidiuretic action on the kidney, it also causes vasoconstriction of the peripheral vessels. Acts by binding to vasopressin receptors (V1bR/AVPR1B, V1aR/AVPR1A, and V2R/AVPR2).
Protein Name Vasopressin-Neurophysin 2-Copeptin
Avp-Npii Cleaved Into - Arg-Vasopressin
Arginine-Vasopressin - Neurophysin 2
Neurophysin-Ii - Copeptin
Database Links Reactome: R-HSA-1368108
Reactome: R-HSA-388479
Reactome: R-HSA-416476
Reactome: R-HSA-418555
Reactome: R-HSA-432040
Reactome: R-HSA-5619099
Reactome: R-HSA-879518
Reactome: R-HSA-8856825
Reactome: R-HSA-8856828
Reactome: R-HSA-9036092
Cellular Localisation Secreted
Alternative Antibody Names Anti-Vasopressin-Neurophysin 2-Copeptin antibody
Anti-Avp-Npii Cleaved Into - Arg-Vasopressin antibody
Anti-Arginine-Vasopressin - Neurophysin 2 antibody
Anti-Neurophysin-Ii - Copeptin antibody
Anti-AVP antibody
Anti-ARVP antibody
Anti-VP antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance