Western blot analysis of extracts of various cell lines, using PPP3CC antibody (STJ110025) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-PPP3CC antibody (373-512) (STJ110025)

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STJ110025
€140.63 - €655.63
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PPP3CC
Gene ID: 5533
Uniprot ID: PP2BC_HUMAN
Immunogen Region: 373-512
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 373-512 of human PPP3CC (NP_005596.2).
Immunogen Sequence: LISDDEAEGSTTVRKEIIRN KIRAIGKMARVFSILRQESE SVLTLKGLTPTGTLPLGVLS GGKQTIETATVEAVEAREAI RGFSLQHKIRSFEEARGLDR INERMPPRKDSIHAGGPMKS VTSAHSHAAHRSDQGKKAHS
Tissue Specificity Testis.
Function Calcium-dependent, calmodulin-stimulated protein phosphatase which plays an essential role in the transduction of intracellular Ca(2+)-mediated signals. Dephosphorylates and activates transcription factor NFATC1. Dephosphorylates and inactivates transcription factor ELK1. Dephosphorylates DARPP32.
Protein Name Serine/Threonine-Protein Phosphatase 2b Catalytic Subunit Gamma Isoform
Cam-Prp Catalytic Subunit
Calcineurin - Testis-Specific Catalytic Subunit
Calmodulin-Dependent Calcineurin A Subunit Gamma Isoform
Database Links Reactome: R-HSA-111447
Reactome: R-HSA-180024
Cellular Localisation Mitochondrion
Localizes In The Mitochondria In A Spata33-Dependent Manner
Alternative Antibody Names Anti-Serine/Threonine-Protein Phosphatase 2b Catalytic Subunit Gamma Isoform antibody
Anti-Cam-Prp Catalytic Subunit antibody
Anti-Calcineurin - Testis-Specific Catalytic Subunit antibody
Anti-Calmodulin-Dependent Calcineurin A Subunit Gamma Isoform antibody
Anti-PPP3CC antibody
Anti-CALNA3 antibody
Anti-CNA3 antibody

Information sourced from Uniprot.org

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