Anti-PPP3CC antibody (373-512) (STJ110025)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal PPP3CC (373-512) antibody for use in WB and ELISA in mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PPP3CC |
| Gene ID | 5533 |
| Uniprot ID | PP2BC_HUMAN |
| Immunogen Region | 373-512 |
| Immunogen Sequence | LISDDEAEGSTTVRKEIIRN KIRAIGKMARVFSILRQESE SVLTLKGLTPTGTLPLGVLS GGKQTIETATVEAVEAREAI RGFSLQHKIRSFEEARGLDR INERMPPRKDSIHAGGPMKS VTSAHSHAAHRSDQGKKAHS |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 373-512 of human PPP3CC (NP_005596.2). |
Additional Info
| Tissue Specificity | Testis. |
| Function | Calcium-dependent, calmodulin-stimulated protein phosphatase which plays an essential role in the transduction of intracellular Ca(2+)-mediated signals. Dephosphorylates and activates transcription factor NFATC1. Dephosphorylates and inactivates transcription factor ELK1. Dephosphorylates DARPP32. |
| Protein Name | Serine/Threonine-Protein Phosphatase 2b Catalytic Subunit Gamma IsoformCam-Prp Catalytic SubunitCalcineurin - Testis-Specific Catalytic SubunitCalmodulin-Dependent Calcineurin A Subunit Gamma Isoform |
| Database Links | Reactome: R-HSA-111447Reactome: R-HSA-180024 |
| Cellular Localisation | MitochondrionLocalizes In The Mitochondria In A Spata33-Dependent Manner |
| Alternative Antibody Names | Anti-Serine/Threonine-Protein Phosphatase 2b Catalytic Subunit Gamma Isoform antibodyAnti-Cam-Prp Catalytic Subunit antibodyAnti-Calcineurin - Testis-Specific Catalytic Subunit antibodyAnti-Calmodulin-Dependent Calcineurin A Subunit Gamma Isoform antibodyAnti-PPP3CC antibodyAnti-CALNA3 antibodyAnti-CNA3 antibody |
Information sourced from Uniprot.org