Anti-PPP2R2A antibody (STJA0008024)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human PPP2R2A
General Information
| Short Description | Rabbit polyclonal anti-Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PPP2R2A |
| Gene ID | 5520 |
| Uniprot ID | 2ABA_HUMAN |
| Immunogen | Synthesized peptide derived from human PPP2R2A |
| Specificity | This antibody detects endogenous levels of PPP2R2A at Human, Mouse, Rat |
Additional Info
| Function | Substrate-recognition subunit of protein phosphatase 2A (PP2A) that plays a key role in cell cycle by controlling mitosis entry and exit. Involved in chromosome clustering during late mitosis by mediating dephosphorylation of MKI67. Essential for serine/threonine-protein phosphatase 2A-mediated dephosphorylation of WEE1, preventing its ubiquitin-mediated proteolysis, increasing WEE1 protein levels, and promoting the G2/M checkpoint. |
| Protein Name | Serine/Threonine-Protein Phosphatase 2a 55 Kda Regulatory Subunit B Alpha IsoformPp2a Subunit B Isoform B55-AlphaB55Pp2a Subunit B Isoform Pr55-AlphaPp2a Subunit B Isoform R2-AlphaPp2a Subunit B Isoform Alpha |
| Database Links | Reactome: R-HSA-2995383Reactome: R-HSA-69231Reactome: R-HSA-69273Reactome: R-HSA-975957Reactome: R-HSA-9860927 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Serine/Threonine-Protein Phosphatase 2a 55 Kda Regulatory Subunit B Alpha Isoform antibodyAnti-Pp2a Subunit B Isoform B55-Alpha antibodyAnti-B55 antibodyAnti-Pp2a Subunit B Isoform Pr55-Alpha antibodyAnti-Pp2a Subunit B Isoform R2-Alpha antibodyAnti-Pp2a Subunit B Isoform Alpha antibodyAnti-PPP2R2A antibody |
Information sourced from Uniprot.org