Anti-PPP2R2A antibody (STJA0008024)

SKU:
STJA0008024

Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PPP2R2A
Gene ID: 5520
Uniprot ID: 2ABA_HUMAN
Specificity: This antibody detects endogenous levels of PPP2R2A at Human, Mouse, Rat
Immunogen: Synthesized peptide derived from human PPP2R2A
Function The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. Essential for serine/threonine-protein phosphatase 2A-mediated dephosphorylation of WEE1, preventing its ubiquitin-mediated proteolysis, increasing WEE1 protein levels, and promoting the G2/M checkpoint.
Protein Name Serine/Threonine-Protein Phosphatase 2a 55 Kda Regulatory Subunit B Alpha Isoform
Pp2a Subunit B Isoform B55-Alpha
Pp2a Subunit B Isoform Pr55-Alpha
Pp2a Subunit B Isoform R2-Alpha
Pp2a Subunit B Isoform Alpha
Database Links Reactome: R-HSA-2995383
Reactome: R-HSA-69231
Reactome: R-HSA-69273
Reactome: R-HSA-975957
Alternative Antibody Names Anti-Serine/Threonine-Protein Phosphatase 2a 55 Kda Regulatory Subunit B Alpha Isoform antibody
Anti-Pp2a Subunit B Isoform B55-Alpha antibody
Anti-Pp2a Subunit B Isoform Pr55-Alpha antibody
Anti-Pp2a Subunit B Isoform R2-Alpha antibody
Anti-Pp2a Subunit B Isoform Alpha antibody
Anti-PPP2R2A antibody

Information sourced from Uniprot.org

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