Anti-PPP1R13L antibody (STJA0007243)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human iASPP
General Information
| Short Description | Rabbit polyclonal anti-RelA-associated inhibitor for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PPP1R13L |
| Gene ID | 10848 |
| Uniprot ID | IASPP_HUMAN |
| Immunogen | Synthesized peptide derived from human iASPP |
| Specificity | This antibody detects endogenous levels of iASPP at Human, Mouse |
Additional Info
| Function | Regulator that plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins. Blocks transcription of HIV-1 virus by inhibiting the action of both NF-kappa-B and SP1. Also inhibits p53/TP53 function, possibly by preventing the association between p53/TP53 and ASPP1 or ASPP2, and therefore suppressing the subsequent activation of apoptosis. Is involved in NF-kappa-B dependent negative regulation of inflammatory response. |
| Protein Name | Rela-Associated InhibitorInhibitor Of Aspp ProteinProtein IasppNfkb-Interacting Protein 1Ppp1r13b-Like Protein |
| Database Links | Reactome: R-HSA-6804759 |
| Cellular Localisation | CytoplasmNucleusPredominantly Cytoplasmic But Also Nuclear |
| Alternative Antibody Names | Anti-Rela-Associated Inhibitor antibodyAnti-Inhibitor Of Aspp Protein antibodyAnti-Protein Iaspp antibodyAnti-Nfkb-Interacting Protein 1 antibodyAnti-Ppp1r13b-Like Protein antibodyAnti-PPP1R13L antibodyAnti-IASPP antibodyAnti-NKIP1 antibodyAnti-PPP1R13BL antibodyAnti-RAI antibody |
Information sourced from Uniprot.org