Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-RelA-associated inhibitor is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
PPP1R13L |
Gene ID: |
10848 |
Uniprot ID: |
IASPP_HUMAN |
Specificity: |
This antibody detects endogenous levels of iASPP at Human, Mouse |
Immunogen: |
Synthesized peptide derived from human iASPP |
Function | Regulator that plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins. Blocks transcription of HIV-1 virus by inhibiting the action of both NF-kappa-B and SP1. Also inhibits p53/TP53 function, possibly by preventing the association between p53/TP53 and ASPP1 or ASPP2, and therefore suppressing the subsequent activation of apoptosis. |
Protein Name | Rela-Associated InhibitorInhibitor Of Aspp ProteinProtein IasppNfkb-Interacting Protein 1Ppp1r13b-Like Protein |
Database Links | Reactome: R-HSA-6804759 |
Cellular Localisation | CytoplasmNucleusPredominantly Cytoplasmic But Also Nuclear |
Alternative Antibody Names | Anti-Rela-Associated Inhibitor antibodyAnti-Inhibitor Of Aspp Protein antibodyAnti-Protein Iaspp antibodyAnti-Nfkb-Interacting Protein 1 antibodyAnti-Ppp1r13b-Like Protein antibodyAnti-PPP1R13L antibodyAnti-IASPP antibodyAnti-NKIP1 antibodyAnti-PPP1R13BL antibodyAnti-RAI antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance