| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PPA2 |
| Gene ID: | 27068 |
| Uniprot ID: | IPYR2_HUMAN |
| Immunogen Region: | 33-100 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 33-100 of human PPA2 (NP_008834.3). |
| Immunogen Sequence: | ALYHTEERGQPCSQNYRLFF KNVTGHYISPFHDIPLKVNS KEENGIPMKKARNDEYENLF NMIVEIPR |
| Tissue Specificity | Detected in brain, gastric carcinoma, lung, ovary, skeletal muscle, umbilical cord blood and a cell line derived from kidney proximal tubule epithelium. |
| Function | Hydrolyzes inorganic pyrophosphate. This activity is essential for correct regulation of mitochondrial membrane potential, and mitochondrial organization and function. |
| Protein Name | Inorganic Pyrophosphatase 2 - MitochondrialPyrophosphatase Sid6-306Pyrophosphate Phospho-Hydrolase 2Ppase 2 |
| Database Links | Reactome: R-HSA-379726Reactome: R-HSA-71737 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Inorganic Pyrophosphatase 2 - Mitochondrial antibodyAnti-Pyrophosphatase Sid6-306 antibodyAnti-Pyrophosphate Phospho-Hydrolase 2 antibodyAnti-Ppase 2 antibodyAnti-PPA2 antibodyAnti-HSPC124 antibody |
Information sourced from Uniprot.org