Anti-PPA2 antibody (33-100) (STJ118264)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal PPA2 (33-100) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PPA2 |
| Gene ID | 27068 |
| Uniprot ID | IPYR2_HUMAN |
| Immunogen Region | 33-100 |
| Immunogen Sequence | ALYHTEERGQPCSQNYRLFF KNVTGHYISPFHDIPLKVNS KEENGIPMKKARNDEYENLF NMIVEIPR |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 33-100 of human PPA2 (NP_008834.3). |
Additional Info
| Tissue Specificity | Detected in brain, gastric carcinoma, lung, ovary, skeletal muscle, umbilical cord blood and a cell line derived from kidney proximal tubule epithelium. |
| Function | Hydrolyzes inorganic pyrophosphate. This activity is essential for correct regulation of mitochondrial membrane potential, and mitochondrial organization and function. |
| Protein Name | Inorganic Pyrophosphatase 2 - MitochondrialPyrophosphatase Sid6-306Pyrophosphate Phospho-Hydrolase 2Ppase 2 |
| Database Links | Reactome: R-HSA-379726Reactome: R-HSA-71737 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Inorganic Pyrophosphatase 2 - Mitochondrial antibodyAnti-Pyrophosphatase Sid6-306 antibodyAnti-Pyrophosphate Phospho-Hydrolase 2 antibodyAnti-Ppase 2 antibodyAnti-PPA2 antibodyAnti-HSPC124 antibody |
Information sourced from Uniprot.org