Anti-POMT1 antibody (310-550) (STJ112319)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal POMT1 (310-550) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:1000-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | POMT1 |
| Gene ID | 10585 |
| Uniprot ID | POMT1_HUMAN |
| Immunogen Region | 310-550 |
| Immunogen Sequence | VFGKPVPCWLHSHQDTYPMI YENGRGSSHQQQVTCYPFKD VNNWWIVKDPRRHQLVVSSP PRPVRHGDMVQLVHGMTTRS LNTHDVAAPLSPHSQEVSCY IDYNISMPAQNLWRLEIVNR GSDTDVWKTILSEVRFVHVN TSAVLKLSGAHLPDWGYRQL EIVGEKLSRGYHGSTVWNVE EHRYGASQEQRERERELHSP AQVDVSRNLSFMARFSELQW RMLALRSDDSEHKYSSSPL |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 310-550 of human POMT1 (NP_001070833.1). |
Additional Info
| Tissue Specificity | Widely expressed. Highly expressed in testis, heart and pancreas. Detected at lower levels in kidney, skeletal muscle, brain, placenta, lung and liver. |
| Function | Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. Coexpression of both POMT1 and POMT2 is necessary for enzyme activity, expression of either POMT1 or POMT2 alone is insufficient. Essentially dedicated to O-mannosylation of alpha-DAG1 and few other proteins but not of cadherins and protocaherins. |
| Protein Name | Protein O-Mannosyl-Transferase 1Dolichyl-Phosphate-Mannose--Protein Mannosyltransferase 1 |
| Database Links | Reactome: R-HSA-5083629Reactome: R-HSA-5083633Reactome: R-HSA-5173105 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Protein O-Mannosyl-Transferase 1 antibodyAnti-Dolichyl-Phosphate-Mannose--Protein Mannosyltransferase 1 antibodyAnti-POMT1 antibody |
Information sourced from Uniprot.org