| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-POMT1 (310-550) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:1000-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
POMT1 |
| Gene ID: |
10585 |
| Uniprot ID: |
POMT1_HUMAN |
| Immunogen Region: |
310-550 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 310-550 of human POMT1 (NP_001070833.1). |
| Immunogen Sequence: |
VFGKPVPCWLHSHQDTYPMI YENGRGSSHQQQVTCYPFKD VNNWWIVKDPRRHQLVVSSP PRPVRHGDMVQLVHGMTTRS LNTHDVAAPLSPHSQEVSCY IDYNISMPAQNLWRLEIVNR GSDTDVWKTILSEVRFVHVN TSAVLKLSGAHLPDWGYRQL EIVGEKLSRGYHGSTVWNVE EHRYGASQEQRERERELHSP AQVDVSRNLSFMARFSELQW RMLALRSDDSEHKYSSSPL |
| Tissue Specificity | Widely expressed. Highly expressed in testis, heart and pancreas. Detected at lower levels in kidney, skeletal muscle, brain, placenta, lung and liver. |
| Function | Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. Coexpression of both POMT1 and POMT2 is necessary for enzyme activity, expression of either POMT1 or POMT2 alone is insufficient. Essentially dedicated to O-mannosylation of alpha-DAG1 and few other proteins but not of cadherins and protocaherins. |
| Protein Name | Protein O-Mannosyl-Transferase 1Dolichyl-Phosphate-Mannose--Protein Mannosyltransferase 1 |
| Database Links | Reactome: R-HSA-5083629Reactome: R-HSA-5083633Reactome: R-HSA-5173105 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Protein O-Mannosyl-Transferase 1 antibodyAnti-Dolichyl-Phosphate-Mannose--Protein Mannosyltransferase 1 antibodyAnti-POMT1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
