Anti-POMGNT2 antibody (160-340) (STJ116729)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal POMGNT2 (160-340) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | POMGNT2 |
| Gene ID | 84892 |
| Uniprot ID | PMGT2_HUMAN |
| Immunogen Region | 160-340 |
| Immunogen Sequence | NPDNLMHVFHDDLLPLFYTL RQFPGLAHEARLFFMEGWGE GAHFDLYKLLSPKQPLLRAQ LKTLGRLLCFSHAFVGLSKI TTWYQYGFVQPQGPKANILV SGNEIRQFARFMTEKLNVSH TGVPLGEEYILVFSRTQNRL ILNEAELLLALAQEFQMKTV TVSLEDHTFADVVRLVSNAS M |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 160-340 of human POMGNT2 (NP_116195.2). |
Additional Info
| Tissue Specificity | Highly expressed in the brain, muscle, heart, and kidney in both fetus and adult. In the brain, highest expression in the cortex and cerebellum. Highly expressed in the pancreas. |
| Function | O-linked mannose beta-1,4-N-acetylglucosaminyltransferase that transfers UDP-N-acetyl-D-glucosamine to the 4-position of the mannose to generate N-acetyl-D-glucosamine-beta-1,4-O-D-mannosylprotein. Involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. |
| Protein Name | Protein O-Linked-Mannose Beta-1 -4-N-Acetylglucosaminyltransferase 2Pomgnt2Extracellular O-Linked N-Acetylglucosamine Transferase-LikeGlycosyltransferase-Like Domain-Containing Protein 2 |
| Database Links | Reactome: R-HSA-5173105 |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Protein O-Linked-Mannose Beta-1 -4-N-Acetylglucosaminyltransferase 2 antibodyAnti-Pomgnt2 antibodyAnti-Extracellular O-Linked N-Acetylglucosamine Transferase-Like antibodyAnti-Glycosyltransferase-Like Domain-Containing Protein 2 antibodyAnti-POMGNT2 antibodyAnti-AGO61 antibodyAnti-C3orf39 antibodyAnti-EOGTL antibodyAnti-GTDC2 antibody |
Information sourced from Uniprot.org