• Western blot with Anti-PNPLA3 Antibody (STJ502570) on A) Rat liver, B) Mouse kidney. Antibody at 1:500 dilution in buffer.

Anti-PNPLA3 antibody (150-200) (STJ502570)

SKU:
STJ502570-100

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Host: Rabbit
Applications: DB/ELISA/IP/WB
Reactivity: Bovine/Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-PNPLA3 (150-200) is suitable for use in Dot Blot, ELISA, Immunoprecipitation and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Purification: Affinity Purified
Concentration: 0.68 µg/µl
Dilution Range: WB: 1:500
DB: 1:4, 000
ELISA: 1:4, 000
IP: 1:150
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: PNPLA3
Gene ID: 80339
Uniprot ID: PLPL3_HUMAN
Immunogen Region: 150-200
Immunogen: Synthetic peptide taken within amino acid region 150-200 on human Patatin-like phospholipase domain-containing protein 3.
Function Specifically catalyzes coenzyme A (CoA)-dependent acylation of 1-acyl-sn-glycerol 3-phosphate (2-lysophosphatidic acid/LPA) to generate phosphatidic acid (PA), an important metabolic intermediate and precursor for both triglycerides and glycerophospholipids. Does not esterify other lysophospholipids. Acyl donors are long chain (at least C16) fatty acyl-CoAs: arachidonoyl-CoA, linoleoyl-CoA, oleoyl-CoA and at a lesser extent palmitoyl-CoA. Additionally possesses low triacylglycerol lipase and CoA-independent acylglycerol transacylase activities and thus may play a role in acyl-chain remodeling of triglycerides. In vitro may express hydrolytic activity against glycerolipids triacylglycerol, diacylglycerol and monoacylglycerol, with a strong preference for oleic acid as the acyl moiety. However, the triacylglycerol hydrolase activity is controversial and may be very low. Possesses phospholipase A2 activity.
Protein Name 1-Acylglycerol-3-Phosphate O-Acyltransferase Pnpla3
Acylglycerol Transacylase
Adiponutrin
Adpn
Calcium-Independent Phospholipase A2-Epsilon
Ipla2-Epsilon
Lysophosphatidic Acid Acyltransferase
Patatin-Like Phospholipase Domain-Containing Protein 3
Database Links Reactome: R-HSA-1482883
Cellular Localisation Membrane
Single-Pass Type Ii Membrane Protein
Lipid Droplet
Alternative Antibody Names Anti-1-Acylglycerol-3-Phosphate O-Acyltransferase Pnpla3 antibody
Anti-Acylglycerol Transacylase antibody
Anti-Adiponutrin antibody
Anti-Adpn antibody
Anti-Calcium-Independent Phospholipase A2-Epsilon antibody
Anti-Ipla2-Epsilon antibody
Anti-Lysophosphatidic Acid Acyltransferase antibody
Anti-Patatin-Like Phospholipase Domain-Containing Protein 3 antibody
Anti-PNPLA3 antibody
Anti-ADPN antibody
Anti-C22orf20 antibody

Information sourced from Uniprot.org

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