| Host: | Rabbit |
| Applications: | IHC/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-PKD1L3 is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Lyophilised |
| Purification: | IgG purified |
| Dilution Range: | IHC, WB. A dilution of 1:1000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Storage Instruction: | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: | PKD1L3 |
| Gene ID: | 342372 |
| Uniprot ID: | PK1L3_HUMAN |
| Specificity: | Specific for PKD1L3. |
| Immunogen: | A synthetic peptide from human PKD1L3 conjugated to blue carrier protein was used as the antigen. |
| Post Translational Modifications | Autoproteolytically processed at the GPS region of the GAIN-B domain.this cleavage modulates receptor activity. |
| Function | Component of a calcium channel. May act as a sour taste receptor by forming a calcium channel with PKD1L3 in gustatory cells.however, its contribution to sour taste perception is unclear in vivo and may be indirect. |
| Protein Name | Polycystin-1-Like Protein 3Polycystin-1l3Pc1-Like 3 ProteinPolycystic Kidney Disease Protein 1-Like 3 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinInteraction With Pkd2l1 Is Required For Localization To The Cell Membrane |
| Alternative Antibody Names | Anti-Polycystin-1-Like Protein 3 antibodyAnti-Polycystin-1l3 antibodyAnti-Pc1-Like 3 Protein antibodyAnti-Polycystic Kidney Disease Protein 1-Like 3 antibodyAnti-PKD1L3 antibody |
Information sourced from Uniprot.org