Anti-PKD1L3 antibody (STJ13101574)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from human PKD1L3 conjugated to blue carrier protein was used as the antigen.
General Information
| Short Description | Rabbit polyclonal anti-PKD1L3 for use in IHC and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC, WB. A dilution of 1:1000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20ยฐC for long term storage and refrigerated at 2-8ยฐC for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | PKD1L3 |
| Gene ID | 342372 |
| Uniprot ID | PK1L3_HUMAN |
| Immunogen | A synthetic peptide from human PKD1L3 conjugated to blue carrier protein was used as the antigen. |
| Specificity | Specific for PKD1L3. |
Additional Info
| Post Translational Modifications | Autoproteolytically processed at the GPS region of the GAIN-B domain.this cleavage modulates receptor activity. |
| Function | Pore-forming subunit of a heterotetrameric, non-selective cation channel that is permeable to Ca(2+). Also shows permeability towards NA(1+), K(+) and Mg(2+). Heterotetrameric complex channel is activated by external low pH and Ca(2+), but opens only when the extracellular pH rises again and after the removal of acid stimulus. May act as a sour taste receptor in gustatory cells.however, its contribution to sour taste perception is unclear in vivo and may be indirect. |
| Protein Name | Polycystin-1-Like Protein 3Polycystin-1l3Pc1-Like 3 ProteinPolycystic Kidney Disease Protein 1-Like 3 |
| Database Links | |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinInteraction With Pkd2l1 Is Required For Localization To The Cell Membrane |
| Alternative Antibody Names | Anti-Polycystin-1-Like Protein 3 antibodyAnti-Polycystin-1l3 antibodyAnti-Pc1-Like 3 Protein antibodyAnti-Polycystic Kidney Disease Protein 1-Like 3 antibodyAnti-PKD1L3 antibody |
Information sourced from Uniprot.org