• Western blot analysis of extracts of various cell lines, using Pituitary homeobox 2 (PITX2) antibody (STJ25006) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-PITX2 antibody (1-100) (STJ25006)

SKU:
STJ25006

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-PITX2 (1-100) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PITX2
Gene ID: 5308
Uniprot ID: PITX2_HUMAN
Immunogen Region: 1-100
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Pituitary homeobox 2 (PITX2) (NP_000316.2).
Immunogen Sequence: MNCMKGPLHLEHRAAGTKLS AVSSSSCHHPQPLAMASVLA PGQPRSLDSSKHRLEVHTIS DTSSPEAAEKDKSQQGKNED VGAEDPSKKKRQRRQRTHFT
Post Translational Modifications Phosphorylation at Thr-90 impairs its association with the CCND1 mRNA-stabilizing complex thus shortening the half-life of CCND1.
Function Controls cell proliferation in a tissue-specific manner and is involved in morphogenesis. During embryonic development, exerts a role in the expansion of muscle progenitors. May play a role in the proper localization of asymmetric organs such as the heart and stomach. Isoform PTX2C is involved in left-right asymmetry the developing embryo.
Protein Name Pituitary Homeobox 2
All1-Responsive Protein Arp1
Homeobox Protein Pitx2
Paired-Like Homeodomain Transcription Factor 2
Rieg Bicoid-Related Homeobox Transcription Factor
Solurshin
Database Links Reactome: R-HSA-8866906
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Pituitary Homeobox 2 antibody
Anti-All1-Responsive Protein Arp1 antibody
Anti-Homeobox Protein Pitx2 antibody
Anti-Paired-Like Homeodomain Transcription Factor 2 antibody
Anti-Rieg Bicoid-Related Homeobox Transcription Factor antibody
Anti-Solurshin antibody
Anti-PITX2 antibody
Anti-ARP1 antibody
Anti-RGS antibody
Anti-RIEG antibody
Anti-RIEG1 antibody

Information sourced from Uniprot.org

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