| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Phosphatidylserine decarboxylase proenzyme, mitochondrial is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PISD |
| Gene ID: | 23761 |
| Uniprot ID: | PISD_HUMAN |
| Specificity: | This antibody detects endogenous levels of PISD at Human, Mouse |
| Immunogen: | Synthesized peptide derived from human PISD |
| Function | Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. May be involved in lipid droplet biogenesis at the endoplasmic reticulum membrane. |
| Protein Name | Phosphatidylserine Decarboxylase Proenzyme - Mitochondrial Cleaved Into - Phosphatidylserine Decarboxylase Beta Chain - Phosphatidylserine Decarboxylase Alpha Chain |
| Database Links | Reactome: R-HSA-1483213 |
| Cellular Localisation | Phosphatidylserine Decarboxylase Beta Chain: Mitochondrion Inner Membrane Single-Pass Membrane Protein Intermembrane Side Phosphatidylserine Decarboxylase Alpha Chain: Mitochondrion Inner Membrane Peripheral Membrane Protein Cytoplasm Anchored To The Mitochondrial Inner Membrane Through Its Interaction With The Integral Membrane Beta Chain Isoform 1: Mitochondrion Inner Membrane Isoform 2: Mitochondrion Inner Membrane Lipid Droplet Predominantly Localizes To Lipid Droplets In Lipid-Replete Conditions And To Mitochondria In Lipid-Deplete Conditions |
| Alternative Antibody Names | Anti-Phosphatidylserine Decarboxylase Proenzyme - Mitochondrial Cleaved Into - Phosphatidylserine Decarboxylase Beta Chain - Phosphatidylserine Decarboxylase Alpha Chain antibody Anti-PISD antibody |
Information sourced from Uniprot.org