Anti-PISD antibody (STJA0007825)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human PISD
General Information
| Short Description | Rabbit polyclonal anti-Phosphatidylserine decarboxylase proenzyme, mitochondrial for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PISD |
| Gene ID | 23761 |
| Uniprot ID | PISD_HUMAN |
| Immunogen | Synthesized peptide derived from human PISD |
| Specificity | This antibody detects endogenous levels of PISD at Human, Mouse |
Additional Info
| Function | Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. May be involved in lipid droplet biogenesis at the endoplasmic reticulum membrane. |
| Protein Name | Phosphatidylserine Decarboxylase Proenzyme - Mitochondrial Cleaved Into - Phosphatidylserine Decarboxylase Beta Chain - Phosphatidylserine Decarboxylase Alpha Chain |
| Database Links | Reactome: R-HSA-1483213 |
| Cellular Localisation | Phosphatidylserine Decarboxylase Beta Chain: Mitochondrion Inner MembraneSingle-Pass Membrane ProteinIntermembrane SidePhosphatidylserine Decarboxylase Alpha Chain: Mitochondrion Inner MembranePeripheral Membrane ProteinCytoplasmAnchored To The Mitochondrial Inner Membrane Through Its Interaction With The Integral Membrane Beta ChainIsoform 1: Mitochondrion Inner MembraneIsoform 2: Mitochondrion Inner MembraneLipid DropletPredominantly Localizes To Lipid Droplets In Lipid-Replete ConditionsAnd To Mitochondria In Lipid-Deplete Conditions |
| Alternative Antibody Names | Anti-Phosphatidylserine Decarboxylase Proenzyme - Mitochondrial Cleaved Into - Phosphatidylserine Decarboxylase Beta Chain - Phosphatidylserine Decarboxylase Alpha Chain antibodyAnti-PISD antibody |
Information sourced from Uniprot.org