Anti-PIH1D1 antibody (1-290) (STJ115672)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal PIH1D1 (1-290) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PIH1D1 |
| Gene ID | 55011 |
| Uniprot ID | PIHD1_HUMAN |
| Immunogen Region | 1-290 |
| Immunogen Sequence | MANPKLLGMGLSEAEAIGAD SARFEELLLQASKELQQAQT TRPESTQIQPQPGFCIKTNS SEGKVFINICHSPSIPPPAD VTEEELLQMLEEDQAGFRIP MSLGEPHAELDAKGQGCTAY DVAVNSDFYRRMQNSDFLRE LVITIAREGLEDKYNLQLNP EWRMMKNRPFMGSISQQNIR SEQRPRIQELGDLYTPAPGR AESGPEKPHLNLWLEAPDLL LAEVDLPKLDGALGLSLEI |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-290 of human PIH1D1 (NP_060386.1). |
Additional Info
| Tissue Specificity | Expressed at low levels in normal mammary epithelial cells (at protein level). Highest expression in lung, leukocyte and placenta. Expressed at lower levels in brain, prostate, colon, heart, small intestine, liver, ovary, pancreas, skeletal muscle, spleen, testis and thymus. |
| Function | Involved in the assembly of C/D box small nucleolar ribonucleoprotein (snoRNP) particles. Recruits the SWI/SNF complex to the core promoter of rRNA genes and enhances pre-rRNA transcription. Mediates interaction of TELO2 with the R2TP complex which is necessary for the stability of MTOR and SMG1. Positively regulates the assembly and activity of the mTORC1 complex. |
| Protein Name | Pih1 Domain-Containing Protein 1Nucleolar Protein 17 Homolog |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Pih1 Domain-Containing Protein 1 antibodyAnti-Nucleolar Protein 17 Homolog antibodyAnti-PIH1D1 antibodyAnti-NOP17 antibody |
Information sourced from Uniprot.org