Anti-PI3 antibody (23-117) (STJ27394)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal PI3 (23-117) antibody for use in WB, IHC-P and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IHC-P:1:100-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PI3 |
| Gene ID | 5266 |
| Uniprot ID | ELAF_HUMAN |
| Immunogen Region | 23-117 |
| Immunogen Sequence | AVTGVPVKGQDTVKGRVPFN GQDPVKGQVSVKGQDKVKAQ EPVKGPVSTKPGSCPIILIR CAMLNPPNRCLKDTDCPGIK KCCEGSCGMACFVPQ |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 23-117 of human PI3 (NP_002629.1). |
Additional Info
| Function | Neutrophil and pancreatic elastase-specific inhibitor of skin. It may prevent elastase-mediated tissue proteolysis. Has been shown to inhibit the alpha-4-beta-2/CHRNA2-CHRNB2 nicotinic acetylcholine receptor and to produce a weak inhibition on Kv11.1/KCNH2/ERG1 and on the transient receptor potential cation channel subfamily V member 1 (TRPV1). |
| Protein Name | ElafinElastase-Specific InhibitorEsiPeptidase Inhibitor 3Pi-3Protease Inhibitor Wap3Skin-Derived AntileukoproteinaseSkalpWap Four-Disulfide Core Domain Protein 14 |
| Database Links | Reactome: R-HSA-6803157Reactome: R-HSA-6809371 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Elafin antibodyAnti-Elastase-Specific Inhibitor antibodyAnti-Esi antibodyAnti-Peptidase Inhibitor 3 antibodyAnti-Pi-3 antibodyAnti-Protease Inhibitor Wap3 antibodyAnti-Skin-Derived Antileukoproteinase antibodyAnti-Skalp antibodyAnti-Wap Four-Disulfide Core Domain Protein 14 antibodyAnti-PI3 antibodyAnti-WAP3 antibodyAnti-WFDC14 antibody |
Information sourced from Uniprot.org