| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Phospho-Tyrosine-protein kinase STYK1-Tyr327 is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
STYK1 |
| Gene ID: |
55359 |
| Uniprot ID: |
STYK1_HUMAN |
| Specificity: |
This antibody detects endogenous levels of STYK1/NOK (Phospho-Tyr327) at Human, Mouse, Rat |
| Immunogen: |
Synthesized peptide derived from human STYK1/NOK (Phospho-Tyr327) |
| Tissue Specificity | Widely expressed. Highly expressed in brain, placenta and prostate. Expressed in tumor cells such as hepatoma cells L-02, cervix carcinoma cells HeLa, ovary cancer cells Ho8910 and chronic myelogenous leukemia cells K-562, but not in other tumor cells such as epidermoid carcinoma (A-431). Undetectable in most normal lung tissues, widely expressed in lung cancers. |
| Function | Probable tyrosine protein-kinase, which has strong transforming capabilities on a variety of cell lines. When overexpressed, it can also induce tumor cell invasion as well as metastasis in distant organs. May act by activating both MAP kinase and phosphatidylinositol 3'-kinases (PI3K) pathways. |
| Protein Name | Tyrosine-Protein Kinase Styk1Novel Oncogene With Kinase DomainProtein Pk-UniqueSerine/Threonine/Tyrosine Kinase 1 |
| Cellular Localisation | MembraneSingle-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Tyrosine-Protein Kinase Styk1 antibodyAnti-Novel Oncogene With Kinase Domain antibodyAnti-Protein Pk-Unique antibodyAnti-Serine/Threonine/Tyrosine Kinase 1 antibodyAnti-STYK1 antibodyAnti-NOK antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
