Anti-Phospho-STYK1-Tyr327 antibody (STJA0010008)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human STYK1/NOK (Phospho-Tyr327)
General Information
| Short Description | Rabbit polyclonal anti-Phospho-Tyrosine-protein kinase STYK1-Tyr327 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | STYK1 |
| Gene ID | 55359 |
| Uniprot ID | STYK1_HUMAN |
| Immunogen | Synthesized peptide derived from human STYK1/NOK (Phospho-Tyr327) |
| Specificity | This antibody detects endogenous levels of STYK1/NOK (Phospho-Tyr327) at Human, Mouse, Rat |
Additional Info
| Tissue Specificity | Widely expressed. Highly expressed in brain, placenta and prostate. Expressed in tumor cells such as hepatoma cells L-02, cervix carcinoma cells HeLa, ovary cancer cells Ho8910 and chronic myelogenous leukemia cells K-562, but not in other tumor cells such as epidermoid carcinoma (A-431). Undetectable in most normal lung tissues, widely expressed in lung cancers. |
| Function | Probable tyrosine protein-kinase, which has strong transforming capabilities on a variety of cell lines. When overexpressed, it can also induce tumor cell invasion as well as metastasis in distant organs. May act by activating both MAP kinase and phosphatidylinositol 3'-kinases (PI3K) pathways. |
| Protein Name | Tyrosine-Protein Kinase Styk1Novel Oncogene With Kinase DomainProtein Pk-UniqueSerine/Threonine/Tyrosine Kinase 1 |
| Database Links | |
| Cellular Localisation | MembraneSingle-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Tyrosine-Protein Kinase Styk1 antibodyAnti-Novel Oncogene With Kinase Domain antibodyAnti-Protein Pk-Unique antibodyAnti-Serine/Threonine/Tyrosine Kinase 1 antibodyAnti-STYK1 antibodyAnti-NOK antibody |
Information sourced from Uniprot.org