Anti-Phospho-PDE4B/C/D-Ser133/119/190 antibody (156-205 aa) (STJ90828)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human PDE4D around the phosphorylation site of Ser190/53 at the amino acid range 156-205
General Information
| Short Description | Rabbit polyclonal anti-Phospho-cAMP-specific 3 NA, 5 cyclic phosphodiesterase 4B and cAMP-specific 3 NA, 5 cyclic phosphodiesterase 4C and cAMP-specific 3 NA, 5 cyclic phosphodiesterase 4D-Ser133/119/190 (156-205 aa) for use in WB, IHC, IF and ELISA |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:20000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PDE4BPDE4D514251445143PDE4B_HUMANPDE4D_HUMANPDE4C_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human PDE4D around the phosphorylation site of Ser190/53 at the amino acid range 156-205 |
| Immunogen Region | 156-205 aa |
| Specificity | Phospho-PDE4B/C/D (S133/119/190) Polyclonal Antibody detects endogenous levels of PDE4B/C/D protein only when phosphorylated at S133/119/190. |
Additional Info
| Function | Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in mediating central nervous system effects of therapeutic agents ranging from antidepressants to antiasthmatic and anti-inflammatory agents. |
| Protein Name | Camp-Specific 3' -5'-Cyclic Phosphodiesterase 4bDpde4Pde32 |
| Database Links | Reactome: R-HSA-180024 |
| Alternative Antibody Names | Anti-Camp-Specific 3' -5'-Cyclic Phosphodiesterase 4b antibodyAnti-Dpde4 antibodyAnti-Pde32 antibodyAnti-PDE4B antibodyAnti-DPDE4 antibody |
Information sourced from Uniprot.org