| Host: | Rabbit |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Phospho-cAMP-specific 3 NA, 5 cyclic phosphodiesterase 4B and cAMP-specific 3 NA, 5 cyclic phosphodiesterase 4C and cAMP-specific 3 NA, 5 cyclic phosphodiesterase 4D-Ser133/119/190 (156-205 aa) is suitable for use in W |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:20000IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PDE4DPDE4B514451425143PDE4D_HUMANPDE4B_HUMANPDE4C_HUMAN |
| Immunogen Region: | 156-205 aa |
| Specificity: | Phospho-PDE4B/C/D (S133/119/190) Polyclonal Antibody detects endogenous levels of PDE4B/C/D protein only when phosphorylated at S133/119/190. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human PDE4D around the phosphorylation site of Ser190/53 at the amino acid range 156-205 |
| Function | Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in mediating central nervous system effects of therapeutic agents ranging from antidepressants to antiasthmatic and anti-inflammatory agents. |
| Protein Name | Camp-Specific 3' -5'-Cyclic Phosphodiesterase 4bDpde4Pde32 |
| Database Links | Reactome: R-HSA-180024 |
| Alternative Antibody Names | Anti-Camp-Specific 3' -5'-Cyclic Phosphodiesterase 4b antibodyAnti-Dpde4 antibodyAnti-Pde32 antibodyAnti-PDE4B antibodyAnti-DPDE4 antibody |
Information sourced from Uniprot.org
