Anti-Phospho-MAX-Ser11 antibody (STJA0009824)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human MAX (Phospho Ser11)
General Information
| Short Description | Rabbit polyclonal anti-Phospho-Protein max-Ser11 for use in WB and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Dilution Range | WB 1:1000-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MAX |
| Gene ID | 4149 |
| Uniprot ID | MAX_HUMAN |
| Immunogen | Synthesized peptide derived from human MAX (Phospho Ser11) |
| Specificity | This antibody detects endogenous levels of Human, Mouse, Rat MAX (Phospho Ser11) |
Additional Info
| Tissue Specificity | High levels found in the brain, heart and lung while lower levels are seen in the liver, kidney and skeletal muscle. |
| Post Translational Modifications | Reversible lysine acetylation might regulate the nuclear-cytoplasmic shuttling of specific Max complexes. |
| Function | Transcription regulator. Forms a sequence-specific DNA-binding protein complex with MYC or MAD which recognizes the core sequence 5'-CACGATG-3'. The MYC:MAX complex is a transcriptional activator, whereas the MAD:MAX complex is a repressor. May repress transcription via the recruitment of a chromatin remodeling complex containing H3 'Lys-9' histone methyltransferase activity. Represses MYC transcriptional activity from E-box elements. |
| Protein Name | Protein MaxClass D Basic Helix-Loop-Helix Protein 4Bhlhd4Myc-Associated Factor X |
| Database Links | Reactome: R-HSA-1362277Reactome: R-HSA-69202Reactome: R-HSA-69656Reactome: R-HSA-8953750 |
| Cellular Localisation | NucleusCell ProjectionDendrite |
| Alternative Antibody Names | Anti-Protein Max antibodyAnti-Class D Basic Helix-Loop-Helix Protein 4 antibodyAnti-Bhlhd4 antibodyAnti-Myc-Associated Factor X antibodyAnti-MAX antibodyAnti-BHLHD4 antibody |
Information sourced from Uniprot.org