| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Phospho-Protein max-Ser11 is suitable for use in Western Blot and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:1000-2000ELISA 1:5000-20000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MAX |
| Gene ID: |
4149 |
| Uniprot ID: |
MAX_HUMAN |
| Specificity: |
This antibody detects endogenous levels of Human, Mouse, Rat MAX (Phospho Ser11) |
| Immunogen: |
Synthesized peptide derived from human MAX (Phospho Ser11) |
| Tissue Specificity | High levels found in the brain, heart and lung while lower levels are seen in the liver, kidney and skeletal muscle. |
| Post Translational Modifications | Reversible lysine acetylation might regulate the nuclear-cytoplasmic shuttling of specific Max complexes. |
| Function | Transcription regulator. Forms a sequence-specific DNA-binding protein complex with MYC or MAD which recognizes the core sequence 5'-CACGATG-3'. The MYC:MAX complex is a transcriptional activator, whereas the MAD:MAX complex is a repressor. May repress transcription via the recruitment of a chromatin remodeling complex containing H3 'Lys-9' histone methyltransferase activity. Represses MYC transcriptional activity from E-box elements. |
| Protein Name | Protein MaxClass D Basic Helix-Loop-Helix Protein 4Bhlhd4Myc-Associated Factor X |
| Database Links | Reactome: R-HSA-1362277Reactome: R-HSA-69202Reactome: R-HSA-69656Reactome: R-HSA-8953750 |
| Cellular Localisation | NucleusCell ProjectionDendrite |
| Alternative Antibody Names | Anti-Protein Max antibodyAnti-Class D Basic Helix-Loop-Helix Protein 4 antibodyAnti-Bhlhd4 antibodyAnti-Myc-Associated Factor X antibodyAnti-MAX antibodyAnti-BHLHD4 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
