• Immunohistochemistry analysis of paraffin-embedded human colon carcinoma, using Histone H2A (Phospho-Thr121) Antibody. The picture on the right is blocked with the phospho peptide.
  • Western blot analysis of Hela+UV 5' cells using Phospho-Histone H2A (T121) Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003, Inventbiotech, MN, USA).

Anti-Phospho-Histone H2A-Thr121 antibody (81-130 aa) (STJ91231)

SKU:
STJ91231

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Phospho-Histone H2A type 1 and Histone H2A type 1-B/E and Histone H2A type 1-D and Histone H2A type 1-H and Histone H2A type 2-A and Histone H2A type 3-Thr121 (81-130 aa) is suitable for use in Western Blot, Immunohist
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
IHC 1:100-1:300
ELISA 1:5000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: H2AC11.H2AC13.H2AC15.H2AC16.H2AC17
H2AC4.
Gene ID: 8329/8330/8332/8336/8969
3012/8335
H2A1_HUMAN
H2A1B_HUMAN
H2A3_HUMAN
Immunogen Region: 81-130 aa
Specificity: Phospho-Histone H2A (T121) Polyclonal Antibody detects endogenous levels of Histone H2A protein only when phosphorylated at T121.
Immunogen: The antiserum was produced against synthesized peptide derived from the human Histone H2A around the phosphorylation site of Thr121 at the amino acid range 81-130
Function Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Protein Name Histone H2a Type 1
H2a.1
Histone H2a/Ptl
Database Links Reactome: R-HSA-3214815
Reactome: R-HSA-3214847
Reactome: R-HSA-3214858
Reactome: R-HSA-5689603
Reactome: R-HSA-5689880
Reactome: R-HSA-5689901
Reactome: R-HSA-9609690
Reactome: R-HSA-9610379
Cellular Localisation Nucleus
Chromosome
Alternative Antibody Names Anti-Histone H2a Type 1 antibody
Anti-H2a.1 antibody
Anti-Histone H2a/Ptl antibody
Anti-H2AC11 antibody
Anti-H2AFP antibody
Anti-HIST1H2AG.H2AC13 antibody
Anti-H2AFC antibody
Anti-HIST1H2AI.H2AC15 antibody
Anti-H2AFD antibody
Anti-HIST1H2AK.H2AC16 antibody
Anti-H2AFI antibody
Anti-HIST1H2AL.H2AC17 antibody
Anti-H2AFN antibody
Anti-HIST1H2AM antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance