Anti-Phospho-GAP43-Ser41 antibody (8-57 aa) (STJ90279)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human GAP43 around the phosphorylation site of Ser41 at the amino acid range 8-57
General Information
| Short Description | Rabbit polyclonal anti-Phospho-Neuromodulin-Ser41 (8-57 aa) for use in IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | IF 1:200-1:1000ELISA 1:20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GAP43 |
| Gene ID | 2596 |
| Uniprot ID | NEUM_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human GAP43 around the phosphorylation site of Ser41 at the amino acid range 8-57 |
| Immunogen Region | 8-57 aa |
| Specificity | Phospho-GAP-43 (S41) Polyclonal Antibody detects endogenous levels of GAP-43 protein only when phosphorylated at S41. |
Additional Info
| Function | This protein is associated with nerve growth. It is a major component of the motile 'growth cones' that form the tips of elongating axons. Plays a role in axonal and dendritic filopodia induction. |
| Protein Name | NeuromodulinAxonal Membrane Protein Gap-43Growth-Associated Protein 43Neural Phosphoprotein B-50Pp46 |
| Database Links | Reactome: R-HSA-373760 |
| Cellular Localisation | Cell MembranePeripheral Membrane ProteinCytoplasmic SideCell ProjectionGrowth Cone MembraneSynapseFilopodium MembranePerikaryonDendriteAxonCytoplasmCytoplasmic Surface Of Growth Cone And Synaptic Plasma Membranes |
| Alternative Antibody Names | Anti-Neuromodulin antibodyAnti-Axonal Membrane Protein Gap-43 antibodyAnti-Growth-Associated Protein 43 antibodyAnti-Neural Phosphoprotein B-50 antibodyAnti-Pp46 antibodyAnti-GAP43 antibody |
Information sourced from Uniprot.org