| Short Description : | Rabbit polyclonal anti-Phospho-Tissue factor-Ser290 (246-295 aa) for use in WB, IHC, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC/IF/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:20000IF 1:50-200 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | F3 |
| Gene ID: | 2152 |
| Uniprot ID: | TF_HUMAN |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human Coagulation Factor III around the phosphorylation site of Ser290 at the amino acid range 246-295 |
| Immunogen Region: | 246-295 aa |
| Specificity: | Phospho-TF (S290) Polyclonal Antibody detects endogenous levels of TF protein only when phosphorylated at S290. |
| Function | Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The TF:VIIa complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. |
| Protein Name | Tissue FactorTfCoagulation Factor IiiThromboplastinCd Antigen Cd142 |
| Database Links | Reactome: R-HSA-140834Reactome: R-HSA-9031628 |
| Cellular Localisation | Isoform 1: MembraneSingle-Pass Type I Membrane ProteinIsoform 2: Secreted |
| Alternative Antibody Names | Anti-Tissue Factor antibodyAnti-Tf antibodyAnti-Coagulation Factor Iii antibodyAnti-Thromboplastin antibodyAnti-Cd Antigen Cd142 antibodyAnti-F3 antibody |
Information sourced from Uniprot.org
