Host: |
Rabbit |
Applications: |
WB/IHC/IF/ELISA |
Reactivity: |
Human/Rat/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Phospho-Tissue factor-Ser290 (246-295 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-1:2000IHC 1:100-1:300ELISA 1:20000IF 1:50-200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
F3 |
Gene ID: |
2152 |
Uniprot ID: |
TF_HUMAN |
Immunogen Region: |
246-295 aa |
Specificity: |
Phospho-TF (S290) Polyclonal Antibody detects endogenous levels of TF protein only when phosphorylated at S290. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from the human Coagulation Factor III around the phosphorylation site of Ser290 at the amino acid range 246-295 |
Function | Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The TF:VIIa complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. |
Protein Name | Tissue FactorTfCoagulation Factor IiiThromboplastinCd Antigen Cd142 |
Database Links | Reactome: R-HSA-140834Reactome: R-HSA-9031628 |
Cellular Localisation | Isoform 1: MembraneSingle-Pass Type I Membrane ProteinIsoform 2: Secreted |
Alternative Antibody Names | Anti-Tissue Factor antibodyAnti-Tf antibodyAnti-Coagulation Factor Iii antibodyAnti-Thromboplastin antibodyAnti-Cd Antigen Cd142 antibodyAnti-F3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance