• Western blot analysis of lysates from K562 cells treated with insulin 0.01U/ml 15', using p57 Kip2 (Phospho-Thr310) Antibody. The lane on the right is blocked with the phospho peptide.
  • Immunofluorescence analysis of HUVEC cells treated with serum 20% 30', using p57 Kip2 (Phospho-Thr310) Antibody. The picture on the right is blocked with the phospho peptide.
  • Immunohistochemistry analysis of paraffin-embedded human placenta, using p57 Kip2 (Phospho-Thr310) Antibody. The picture on the right is blocked with the phospho peptide.
  • Enzyme-Linked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phosphopeptide (Phospho-left) and Non-Phosphopeptide (Phospho-right), using p57 Kip2 (Phospho-Thr310) Antibody

Anti-Phospho-CDKN1C-Thr310 antibody (267-316 aa) (STJ91087)

SKU:
STJ91087

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Phospho-Cyclin-dependent kinase inhibitor 1C-Thr310 (267-316 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:10000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CDKN1C
Gene ID: 1028
Uniprot ID: CDN1C_HUMAN
Immunogen Region: 267-316 aa
Specificity: Phospho-p57 (T310) Polyclonal Antibody detects endogenous levels of p57 protein only when phosphorylated at T310.
Immunogen: The antiserum was produced against synthesized peptide derived from the human p57 Kip2 around the phosphorylation site of Thr310 at the amino acid range 267-316
Function Potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. Negative regulator of cell proliferation. May play a role in maintenance of the non-proliferative state throughout life.
Protein Name Cyclin-Dependent Kinase Inhibitor 1c
Cyclin-Dependent Kinase Inhibitor P57
P57kip2
Database Links Reactome: R-HSA-69231
Reactome: R-HSA-9661069
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Cyclin-Dependent Kinase Inhibitor 1c antibody
Anti-Cyclin-Dependent Kinase Inhibitor P57 antibody
Anti-P57kip2 antibody
Anti-CDKN1C antibody
Anti-KIP2 antibody

Information sourced from Uniprot.org

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