Anti-perilipin-2 antibody (325-425) (STJ11105333)

Name: Anti-perilipin-2 antibody (325-425) (STJ11105333)
SKU: STJ11105333
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⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ11105333

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Short Description	Rabbit polyclonal perilipin-2 (325-425) antibody for use in IHC-P, IF, ICC and ELISA in rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	IHC-P/IF/ICC/ELISA
Host	Rabbit
Reactivity	Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	IHC-P:1:50-1:200 IF/ICC:1:50-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.09% Sodium Azide, 50% Glycerol, pH7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	Plin2
Gene ID	11520
Uniprot ID	PLIN2_MOUSE
Immunogen Region	325-425
Immunogen Sequence	TVLVNAQGLPQNIQDQAKHL GVMAGDIYSVFRNAASFKEV SDGVLTSSKGQLQKMKESLD EVMDYFVNNTPLNWLVGPFY PQSTEVNKASLKVQQSEVKA Q
Specificity	A synthetic peptide corresponding to a sequence within amino acids 325-425 of mouse perilipin-2 (NP_031434.3).

Tissue Specificity	Adipose tissue specific. Expressed abundantly and preferentially in fat pads.
Post Translational Modifications	Acylated.primarily with C14, C16 and C18 fatty acids. Phosphorylation at Tyr-230 by isoform 1 of CHKA (CHKalpha2) promotes dissociation from lipid droplets: dissociation is followed by recruitment of autophagosome machinery to lipid droplets and subsequent lipid droplet lipolysis. Polyubiquitination of Nt-acetylatable A-PLIN2 by MARCHF6 lead to degradation by 26S proteasomes.
Function	Structural component of lipid droplets, which is required for the formation and maintenance of lipid storage droplets.
Protein Name	Perilipin-2 Adipophilin Adipose Differentiation-Related Protein Adrp
Database Links
Cellular Localisation	Membrane Peripheral Membrane Protein Lipid Droplet
Alternative Antibody Names	Anti-Perilipin-2 antibody Anti-Adipophilin antibody Anti-Adipose Differentiation-Related Protein antibody Anti-Adrp antibody Anti-Plin2 antibody Anti-Adfp antibody Anti-Adrp antibody

Information sourced from Uniprot.org