| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Sister chromatid cohesion protein PDS5 homolog A is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PDS5A |
| Gene ID: |
23244 |
| Uniprot ID: |
PDS5A_HUMAN |
| Specificity: |
This antibody detects endogenous levels of PDS5A at Human, Rat |
| Immunogen: |
Synthesized peptide derived from human PDS5A |
| Function | Probable regulator of sister chromatid cohesion in mitosis which may stabilize cohesin complex association with chromatin. May couple sister chromatid cohesion during mitosis to DNA replication. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair. |
| Protein Name | Sister Chromatid Cohesion Protein Pds5 Homolog ACell Proliferation-Inducing Gene 54 ProteinSister Chromatid Cohesion Protein 112Scc-112 |
| Database Links | Reactome: R-HSA-2467813Reactome: R-HSA-2468052Reactome: R-HSA-2470946Reactome: R-HSA-2500257 |
| Cellular Localisation | NucleusAssociated With Chromatin Through Most Of The Cell CycleDissociates From Chromatin In Late ProphaseReassociates During Late Telophase |
| Alternative Antibody Names | Anti-Sister Chromatid Cohesion Protein Pds5 Homolog A antibodyAnti-Cell Proliferation-Inducing Gene 54 Protein antibodyAnti-Sister Chromatid Cohesion Protein 112 antibodyAnti-Scc-112 antibodyAnti-PDS5A antibodyAnti-KIAA0648 antibodyAnti-PDS5 antibodyAnti-PIG54 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
